Biohybrid -Se-S- coupling reactions of an amino acid derived seleninate.
نویسندگان
چکیده
We describe the synthesis of the N-(2-seleninatoethyl) amide of N-Boc-phenylalanine, serving here as a peptide model, and its reductive coupling reactions under mild conditions with unprotected thiouridine and glutathione. Selenosulfide products such as these comprise reversibly conjugated bio-components, and can potentially find uses as probes of biological function, such as enzyme inhibitors, delivery systems, or structural mimics.
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عنوان ژورنال:
- Molecules
دوره 18 2 شماره
صفحات -
تاریخ انتشار 2013